Yamada Hana's fresh start in Tokyo hits a bumpy road. She struggles to make a positive impact at school and is obligated to work for her difficult sister. Hana is then sent on an assignment to aid a man named Haru, known for his habit of groping women and strikingly handsome appearance, adding to her complications. Adding insult to injury, Hana is afflicted with a peculiar condition that to erupts her skin in hives upon any interaction with attractive men.